Faculty Advisor

Heilman, Destin

Faculty Advisor

Srinivasan, Jagan

Abstract

In order to determine if nutrition has an effect on social behaviors, this project looks at C. elegans and their responses to endogenously produced small-molecules called ascarosides. This project involves the classification of behavior using behavior assays and different nutritional states. In particular, the project looks at sex-specific behaviors. It was found that both sexes are attracted to ascr#3 and ascr#8 when well-fed. When starved, males are still attracted to ascr#8 whereas hermaphrodites lose their attraction. Growing males and hermaphrodites on glucose plates do not change their response to ascr#8 in either the fed or starved condition. Using the daf-2 mutant, growing hermaphrodites on glucose plates or agar plates did not elicit a response to ascr#8 in the fed condition.

Publisher

Worcester Polytechnic Institute

Date Accepted

April 2014

Major

Biochemistry

Project Type

Major Qualifying Project

Accessibility

Unrestricted

Advisor Department

Chemistry and Biochemistry

Advisor Department

Biology and Biotechnology

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