In order to determine if nutrition has an effect on social behaviors, this project looks at C. elegans and their responses to endogenously produced small-molecules called ascarosides. This project involves the classification of behavior using behavior assays and different nutritional states. In particular, the project looks at sex-specific behaviors. It was found that both sexes are attracted to ascr#3 and ascr#8 when well-fed. When starved, males are still attracted to ascr#8 whereas hermaphrodites lose their attraction. Growing males and hermaphrodites on glucose plates do not change their response to ascr#8 in either the fed or starved condition. Using the daf-2 mutant, growing hermaphrodites on glucose plates or agar plates did not elicit a response to ascr#8 in the fed condition.
Worcester Polytechnic Institute
Major Qualifying Project
All authors have granted to WPI a nonexclusive royalty-free license to distribute copies of the work, subject to other agreements. Copyright is held by the author or authors, with all rights reserved, unless otherwise noted.
Chemistry and Biochemistry
Biology and Biotechnology