Student Work

Complement Receptor-1 Binding to Erythrocytes Under Normal and Pathological Membrane Deforming Conditions

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In primates, complement-coated invading microbes and immune complexes are efficiently removed from circulation by binding complement receptor-1 (CR1) on erythrocytes, a process known as immune-adherence clearance. This project examines the nature and functionality of complement binding to erythrocytes under normal and pathological conditions. The data identifies key factors associated with the complement-CR1 ligation pathway promoting membrane deformability, helping elucidate a greater understanding of this important, unique erythrocyte function.

  • This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.
Creator
Contributors
Publisher
Identifier
  • E-project-042413-184650
Advisor
Year
  • 2013
Sponsor
Date created
  • 2013-04-24
Location
  • Boston
Resource type
Major
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Last modified
  • 2023-09-20

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