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Major Qualifying Projects from 2018

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ELEXIS Based Screen of Human LIGs with ErbB1,2,4, Andrew D. Brunelle

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Copper Homeostasis is Important for Pathogenesis of Pseudomonas aeruginosa in Caenorhabditis elegans, Tristan B. Cano

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Association of Phospholipase-Cβ1 and Component 3 Promoter of RISC, Samuel James Carley

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Characterizing IQGAP1-C Domain Binding to Phosphoinositides, Christopher Anthony Dallarosa

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Characterization of the Role of Aquaporin-7 in Nematode Acid Survival, Kaye Elizabeth Dandrea

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Formation of Potential Tandem Junction Photovoltaic Materials for Silicon, Benjamin N. Drury

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Analysis of Subcellular Localization of PCV1-VP3 Using Mutant Variants, Lauren A. Farris and Rebekah Grace Johnson

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Membrane Composition Analysis of Caenorhabditis Genus Members, Brianna Christine Heisler

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Diet, Microbiome, and Neurological Diseases, Eiko Iwashita

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Developing a FRET-based Activation Indicator in Ste2p, a Yeast GPCR, Victoria Kathleen Johnson

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Assessing Human Immunodeficiency Virus (HIV) Protease Inhibition with Resistant Variants and Novel Inhibitors, Klajdi Kosovrasti and Mina Henes

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Interaction of Zinc Finger Proteins 146 & 507 with the Transposable Element LINE-1, Eric Christoper Larsen

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Photoelectrochemistry of n-Silicon and Bismuth(III) Iodide, Clare Pennock Masucci

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Generation and Mitigation of Cell Debris in a Manufacturing Scale Disc Stack Centrifuge, Kathryn A. Merritt and Kayla M. Sica

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Effect of Gasdermin D on Pyroptosis in Mouse Macrophages, Colleen E. O'Shea

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Targeting BRG1 to Improve Drug Efficacy in Neuroblastoma, Naomi Otoo

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Establishing a Connection between Alzheimer's Disease and Cellular Energy Transduction, Lily Jane Randle, Nathan McNeill, and Timothy Edward Consedine

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PRMT5 Mediates SREBP1 Independent Hepatic Signaling Networks in Lipid Homeostasis, Katelyne Jean Sibley

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Analysis of Polyelectrolytes and Functionalized Silica for Precious Metal Catalyst Recovery, Amy Elizabeth Toscano and Patrick M. Bresnahan

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Creation of an eGFP-PLCβ1 Fusion Protein Using CRISPR-Cas9 Mutagenesis, Kaitlyn Kathleen Valla

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Bacterial Growth in the Presence of Metal Ions and the Quorum Sensing Molecule, AIP (Auto Inducing Peptide), Jared D. Watson

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Study of Inhibitory Properties of Small Molecule Compounds on Histone Deacetylases, Christofer Mathias Welsh

Major Qualifying Projects from 2017

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The Role of Serotonin in the Avoidance Attenuation Response of C. elegans, Megan Marie Andresano

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Investigating a novel Cu+ storage protein in Pseudomonas aeruginosa, Andrew Steven Baez

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Selective Elimination of Microglia Via the Cre-Lox System, Kyle Alfred Bessette

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Investigating the role of Sec6 and RabE during polarized cell growth in Physcomitrella patens, Allison Marie Butt

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Cytoplasmic Localization of PCV1-VP3 is a CRM1-Independent Function, Christine Elizabeth Carbone and Paul deNyse Burrowes

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Investigation of the Propensity for Self-Association of the N-Terminal Domain of Annexin A2 in the Presence of Anionic Lipids, Abigail Carissa Cornwell

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Chronic Adolescent Exposure to Δ9-THC Alters Cognition, Metabolite Levels, and Inflammatory Profile in Rats, Khahnty Daraphet

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Investigating the Effects of Vps45 Mutations Associated with Severe Congenital Neutropenia on SNARE Interactions, Alexandra M. D'Ordine

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Synthesis and Evaluation of New HIV-1 Protease Inhibitors, Jessica Rose Falci

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Gold - Human Serum Albumin Contrast Agents, Sarah K. Fields

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STUDY OF CSSNBR3, Weiran Gao

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Caenorhabditis elegans: Determining the relationship between srf-6 and nsy-1 in C. elegans, Alexander JianSheng Hu

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Low Temperature Electrolysis of Mixed Metal Oxides, Brittany Marie Kyer, Christian Robert Morneau, Everett Vincent Baker, and Shaun Joseph Bonefas

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Determining the Origin of Fe3+-induced BODIPY Probe Fluorescence in Aqueous Solution, Paige Anne Lamica

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The CRISPR Enzyme Cpf1 as a Tool for Gene Regulation, Kyle Stuart Morrison

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Centriole Amplification causes Resistance to Alisertib, Bernat Navarro Serer

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The Role of Phosphatidylserine as a Scaffold for Lipid/Protein Complexes, Vanesa Pinderi

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The Role of Mechanical Stress on Calcium Signals, Androniqi Qifti

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Photoelectrochemical Voltage vs Back Contact Barrier Heights, Margaret Ann Russell

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Aneurysm Simulation and ELISA Detection in Rabbits, Anna Leigh Schozer and Stephanie Michelle Puckett

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RESPIRATORY TARGETED GENE THERAPY IN AN ALS MOUSE MODEL, Victoria Anne Semple

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Investigation of bulky carboxylic acid and amines as trapping agents for controlling the desorption of molecular guests from a porous metal-organic framework material, U Shwe Thein

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Copper-Catalyzed Weak C-H Bond Amination, Nicholas James Venditto

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Tailored Synthesis of Bi2S3 Thin Film to Enhance Optoelectronic Performance, Zhehao Zhu

Major Qualifying Projects from 2016

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Developing Fluorescent Aminoazobenzene Metal-Organic Frameworks, Mario Enrique Alvarado

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Apoptotic Capabilities of Porcine Circovirus 1 Viral Protein 3 as a Function of Subcellular Localization, Katherine Ann Amato

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Knocking out Alpha-1 Antitrypsin Deficiency: The Characterization of a Novel Mouse Model, Brynn H. Cardozo

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The Effects of Post-Transcriptional Processing on mRNA Stability in M. smegmatis, John Henry de Rivera

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Determining the importance of localization of CAV VP3 and TTV VP3 in selective apoptosis of cancer cells, Fernando Galvez and Jessica Marjorie Desmond

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Synthesis and Biochemical Evaluation of Hepatitis C Virus NS3/4A Protease Inhibitors, Michael James Giroux

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Interactions of Copper Chaperones and Transporters in Sinorhizobium Meliloti, Joshua Daniel Hall

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Synthesis of Porphyrins for Use in Metal-Organic Frameworks (MOFs), Benjamin Carleton Hawks

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Analysis and Synthesis of Novel Inhibitors of MMPs and other Biological Targets, Tamika Taylor Isaac

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Characterizing Impact of Initial Conditions on Fermentation in Two New Grape Wines, Minxue Jia

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Optimization of a Geometry for Single Measurement Air Kerma Strength Calibration Using Monte Carlo Simulations, Erika Kathryn Kollitz

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Incorporating Filastatin into medical plastics to minimize nosocomial fungal infections, Zachary William Lipsky

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Incorporating Filastatin into medical plastics to minimize nosocomial fungal infections, Bonham James Pierce

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The Effects of Targeted RNAi of Multiple RNA Binding Proteins on the Expression Pattern of MEX-3 in the Germline of C. elegans, Rachel Ann Prescott

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Torque Teno Virus: Exploring the Effects of Localization on the Apoptotic Ability of TTV-VP3, Kevin Rawlins Roopcharan, Marya Celina Aherrera, and Rashid Gogen Chatani

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Role of CcoA and HmtA in Pseudomonas aeruginosa, Yi Sun

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Liquid-Semiconductor Surface Interactions of Silicon in a Double Liquid Layer Solar Cell, Jessica Lynne Taylor

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Voltage Induced Variation of Solid Acid Catalyst Acidity, Jonathan Thomas Vardner and Rexford Whittier Hoadley

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Photo-induced Polarization in Light-sensitive Dye Monolayers Measured by Electrical Impedance Spectroscopy, Charles Robert Wentzell

Major Qualifying Projects from 2015

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Photophysical Properties of Bis-DMAC, Daniel Rohan Callahan and Nathaniel Jacob Sweet

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Photophysical Properties of Bis-DMAC, Daniel Rohan Callahan and Nathaniel Jacob Sweet

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Aerobic Processing of Glycerol, Michael Chin

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Low Temperature Dehydration of Alcohols, Sarah Jasmine Desrochers

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Truncation mutagenesis of Porcine Circovirus 1 VP3 uncovers the importance of the C-terminal extended region in inducing apoptosis of human cancer cells, Evgenia Jen Filatava and Phuong Thuy Vu

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Biochemical Characterization of the Interaction between Rab Proteins and Myosin XIa in the moss Physcomitrella patens, Jennifer Mary Garbarino and Sarah Elizabeth Kaptur

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Developing Protonated and Deprotonated Cysteine Side-Chain Parameters for POSSIM Force Field, Anetta Victoria Goldsher

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Improvement of Hard Cider Production, Daniel Gonzalez, Joseph Heath Collins, Lina Tran, and Paul Wei Johnston

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Semiconductor Surface Chemistry, Brian Richard Hamilton

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Physical-Mechanical Properties of Extrudates and Tablets Manufactured thereof, Hannah Elizabeth Hill

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Evaluating Multimerization of Apoptin Homologs, ErinMari Konicki and Nicole Emily Bebrin

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A Study on the Hydrophobicity of Organosilane, Chenming Li and Jingtian Kuang

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Efficient Brewery Sanitation, Jacob Hans Manning, Joshua Michael Palmer, Lauren Elizabeth Morse, and Nicholas F. Deraney

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An Evaluation of the C-H Activation Potential of Palladium Catalysts, Mark Alexander Mantell

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Feel the Burn: Investigating New Sensitizers for Hybrid Dye-Sensitized Solar Cells, Ana Stella Mateo, Edwin Nicholas McGlew, and Sarah Elizabeth Quatieri

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Investigation of PCV1-VP3 Nuclear Export Signal Sequences Using Site-Directed Mutagenesis, Arjun Dav Mathur and Taryn Dawn Roy

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Synthesis and Study of Ligands in Photocage Complexes, Elizabeth Anne Miloscia

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Palladium-Catalyzed Non-Directed C-H Amination of Arenes, Turner David Newton

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Localization Assessment of Novel Nuclear Export Signal Sequence Mutants in PCV1-VP3, Nicholas Abraham Pakatar

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Apoptin and PCV1-VP3 Selectively Induce Apoptosis in Transformed Cells via a Conserved Mechanism Mediated by the Anaphase Promoting Complex, Edward Allen Partlow

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Transparent Healable Materials, Andrew Alexander Portera, Paul Francis Hastings, and Thomas Henry Harless

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Investigation of Triphenylacetic Acid as a Trapping Agent for Sealing Molecular Guests Within Porous Metal-Organic Frameworks, Thomas Michael Rayder

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Investigation of Porphyrin-based MOFs as Porous Hosts for Generating Singlet Oxygen, Francisco Javier Rosales Espinoza and Jiawei Lu

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Investigation of Porphyrin-based MOFs as Porous Hosts for Generating Singlet Oxygen, Francisco Javier Rosales Espinoza and Jiawei Lu

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Systematic Synthesis and Characterization of Cellulase Mimetic Polymers, Andrew James Wood

Major Qualifying Projects from 2014

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An Investigation of the Porcine Circovirus Type 1 Third Viral Protein Nuclear Export Capability Through Fluorescence Microscopy and Rapid Prototyping, Aaron Baruch Benjamin and Timothy Jason Beane

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The Effect of Nutritional State on Social Behaviors in C. elegans, Bethany Suzanne Burke

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Targets of Filastatin, A Chemical Inhibitor of Adhesion and Morphogenesis by Pathogenic Fungi, Damien Joseph Cabral and Michael J. Boyd

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Copper-catalyzed methods for benzylic C-H bond amination, Julia Whitney Darcy

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Modifications of the Self-Immolative Spacer PABOH in Antibody Drug Conjugates, Emily Hilda Domain

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Post-Transcription Regulatory Pathway in C. elegans using Library Mos-1 mediated single copy insertion, Alyssa E. Donohue

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Exploring the role of residues in the intracellular loop of hZIP4 in the binding of zinc, Brian Ronald Doyon

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Hydrothermal Synthesis of Li2MnSiO4: Investigation of the Effects of Different Reaction Conditions, Mengxi Du

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Design of MOFs Containing Porphyrins as Porous Hosts for Generating Singlet Oxygen, Kevin Adam Garcia

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Dual Assay Study of Antisense Transcript Regulation of Meiotic Genes during Mitotic Growth in Schizosaccharomyces pombe, Ryan William Holmes