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Major Qualifying Projects from 2014

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Design of MOFs Containing Porphyrins as Porous Hosts for Generating Singlet Oxygen, Kevin Adam Garcia

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Dual Assay Study of Antisense Transcript Regulation of Meiotic Genes during Mitotic Growth in Schizosaccharomyces pombe, Ryan William Holmes

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OXYGEN GENERATION THROUGH ELECTRICALLY STIMULATED O2 REDUCTION ACROSS ION EXCHANGE MEMBRANES, Daniel Rodgers Jones, Devin A. Churchman, and Raj D. Patel

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Development and analysis of beta glucan particles for high throughput peptide and protein loading, Lindsay S. Jones and Zachary A. Duca

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The Role of p53 Serine 23 in Insulin Resistance, Khanh Thi Nguyen

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Substrate Effects in Hybrid Solar Cells, Eric Martin Oswald

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Investigating the Role of Multimerization in human Torque Teno Virus VP3 Cancer Cell Specific Apoptosis, Michaella Marie Reif and Nicholas John Morassi

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Caenorhabditis elegans: The Search for srf-6 Mutations, Caitlin T. Rush and Nicholas Donald Van Sciver

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A Chemical and Photophysical Analysis of a Push-Pull Compound, Anthony Daniel Salerni

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The POSSIM Force Field in Biochemical Applications, Daniel L. Sigalovsky

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Design and Application of Metal Organic Frameworks Containing Porphyrin Photosensitizers, Andrew Michael Smith and Grace Elizabeth Holliday

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Infrared Spectroscopic Characterization of cPLA2¦Á C2 Domain, Yunqiu Sun

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Palladium Catalyzed Non-directed Aromatic C-H Aminations, Da Teng

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Fusion of Viral Proteins Apoptin and PCV-1 VP3 C-Terminus: A Study of Localization and Induced Specific Apoptosis of Carcinogenic Cells, George H. Tsougranis and Michael J. LeBlanc

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Characterization of Poxvirus A51 Protein Using Yeast-Two Hybrid Screening, Charles Wellington White

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Mapping the binding position of an aptamer on a Z05 DNA polymerase to better understand the complex's stability and compatibility with Hot Start PCR, Danielle Catherine Wisheart

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Development and Analysis of A Novel Nanotherapeutic for the Treatment of Glioblastoma Multiforme, Eileen Susan Wrabel and Joseph Cacaccio

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Aerobic Oxidation Using Air Catalyzed by [Cp*IrCl2]2, Wenbo Wu

Major Qualifying Projects from 2013

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Uncovering the role of HMG box protein TOX in T-cell Acute Lymphoblastic Leukemia, Nouran Saied Abdelfattah

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Optical Properties of ChR2, Stephen Joseph Allen

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Investigation of Metal-Organic Frameworks as Materials for Generating Singlet Oxygen, Codi Hajjar Clark

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Synthesis, Spectroscopic Properties, and Photophysical Properties of (2E,5E)-2-benzylidene-5-(p-dimethylaminocinnamylidene)-cyclopentanone (bdmac), Cara Lynn DiIorio

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Synthesis of New Pharmacophore Scaffolds, Emily Carol Domingue and Matthew Pieter Fusco

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Nanoparticles Stabilized with MPEG-Polylysine Carbamate: Synthesis and Characterization, William Melvin Elmore

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Synthesis of a Paramagnetic Myeloperoxidase Substrate with Superoxide Dismutase Activity, Giancarlo Feula

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Role of XinT2 in Sinorhizobium meliloti, Michael William Gauvin

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Assessment of Similarities Between PCV2 VP3 and CAV Apoptin, Amanda Rose Hanley

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Synthesis and Photophysical Properties of (2E,5E)-2-benzylidene-5-(4-dimethylaminobenzylidene)-cyclopentanone, Laura Elizabeth Hudson

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Three-Dimensional Modeling of Chicken Anemia Virus VP3 and Porcine Circovirus Type 1 VP3, Curtis James Innamorati, Lee Frank Hermsdorf-Krasin, and Samuel Casey Eisenberg

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RNA-binding and Metabolite-mediated Inhibition of Musashi1 Homologs, Emily Stratford Johnson

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The Function of Secondary Argonautes in the ALG-3/4 Sperm Small RNA pathway in C. elegans, Paul Louis Kashmanian

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Interaction Screen of Transmembrane Proteins from the LIG Superfamily, Marinela Mincheva Kirilova

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Synthesis and Evaluation of New HCV NS3/4A Protease Inhibitors, Evangelos Konstantinos Koumbaros

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Surface Modifications Promote Photo-stimulated C2C12 Myotube Contraction, Ross Charles Lagoy

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Synthesis of Analogs to the Steroidal Sapogenin Ruscogenin via Diosgenin, Keegan James Leitz

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A Method of Determining the Relationship Between Copper ATPases and Nitrite Reductase, Robert Van Le

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Mechanism of Near-Infrared Fluorescent Signal Generation in Proteolysis-Sensitive Macromolecular Imaging Probes, Jessica Clotilde Lopez

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Assessment of the Functionality of Nuclear Export Sequences in Porcine Circovirus 1 VP3, Brittany Lee Mahoney and Sarah Theresa Clancey

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Phylogenetic Profile of Copper Homeostasis in Deltaproteobacteria, Courtney Jeanne McCann

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CAN A MORRIS WATER MAZE TEST DISTINGUISH ALZHEIMER’S MICE FROM WT MICE?, Amy Lee Motzer and Ivy Bartolo Castro

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Copper Homeostasis in S. meliloti, Jacquelyn Marie Nemet-Sousa

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Amphetamine Induced Dopamine Transporter Internalization: A Structure/Function Study, Marissa Anne Norton

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Investigation of Argonaute Interactions in C. elegans using Yeast Two - Hybrid, Belinda Uchechi Nwagbara

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Cloning and Expression of H2-D(b) for Future Experimental Studies on its Role in Multiple Sclerosis, Nicole A. Otto

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Design and Optimization of a Sequence-Specific Chimeric DNA-Binding Domain for the Discrimination of Single Nucleotide Polymorphisms, Alexander K. Pankratov

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New Possibilities for Electron-rich Naphthyl Analogs to Facilitate Photocyclic Cycloaddition in the Synthesis of Drug Scaffolds, Nicholas G. Roumas

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Localization Mechanics and Multimerization Ability of Human Torque Teno Virus Viral Protein 3: A Comparison of the Mechanistic Actions of TTV VP3 and Apoptin, Daria Emily Santoro and Devin Leigh Harrison

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Specifying the Structural Boundaries of the Nuclear Localization Sequence in Torque Teno Virus VP3, Bailey Maria Sarber and Emma E. Cady

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Biophysical Characterization of Diacylglycerol Pyrophosphate, Justin Nicholas Siemian

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Investigating Porcine Circovirus Type 2 Viral Protein 3 Multimerization Capabilities, Nicholas J. Teceno

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Low Temperature Template Removal of Fe-ZSM-5, Adam B. Thibault, David Dean Sun, and Nathaniel James Peterson

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Periplasmic Copper Homeostasis in Pseudomonas aeruginosa, Kaleigh Nicole Tomkinson

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Production of Bioliquids from Cellulosic Biomass through Molten Salt Pyrolysis, Christopher Lealand Welsh

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Characterization of the Dye-Sensitized Solar Cell, Zijian Xia

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MUTAGENESIS OF HUMAN SUPERVILLIN’S ADHESION SEQUENCE IDENTIFIES CHANGES IN THE NUMBER, Michelangela Amira Yusif

Major Qualifying Projects from 2012

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Characterizing the DNA-Binding Site Specificities of Cis2His2 Zinc Fingers, Heather Anne Bell

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Construction of a Flash Photolysis System for Excited State Analysis, Zachary Everett Blais

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Nanoparticle Delivery of siRNA, Steven E. Buchholz

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An Analysis of Methods for Detecting Triclosan and Removal of Triclosan from Water Using Activated Carbon and Zeolites, Caitlin Elyse Butler, Jenna Leigh Jaser, and Miranda Aufiero

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A Selective Sensor for Potassium and Ammonium Ions, Carl Lougee Curran

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Hybrid Dye-Sensitized Solar Cells based on Titanium Dioxide and Metal-Phthalocyanines, Amy Do and Nhi Thi Vo-Lextrait

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Drug Synthesis for HCV, Kathleen Suzanne Foust

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Analysis of Germline Specification in C. elegans, Sadie Saludes Josephs

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ADHESION OF SILVER NANOPARTICLES TO GRAPHITE SUBSTRATES, Michael David Judelson and Robert Nicholas Cakounes

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NLR Inflammasome Interactions, Bhavya Kandimalla

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Nanoparticle Delivery of siRNA: Multi-functional Upconverting NaYF4 Nanoparticle siRNA Delivery System for Knockdown of SOD1, a Gene Linked to ALS, Samuel James Kesseli

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Investigation of Cu-MOF Catalyzed Click Reactions, Blaise William Leeber

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A Sensor for a Date-Rape Drug, Incorporated Into a Beverage Container, Jillian L. Morang

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Expression, purification, and characterization of the M3M4 intracellular region of the human Zn2+ transporter protein, ZIP4, Benjamin Robert Morehouse and Emily Joan Rozsahegyi

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Protein Interactions of the Porcine Circovirus Viral Protein 3, Alec E. Morrison and Diego Prentice

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Human Ependymin Neurotrophic Factor Mimetic Increases Alzheimer’s Mice Cognitive Performance in a Morris Water-Maze Test, Mortada Salman Najem and Tayeisha A. Jackson

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Interaction Assay for LIG Superfamily Proteins, Tran Nguyen

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Optimization and Validation of a Pathogenesis Survival Assay with the C. elegans Sterile Mutant Fer-1, Stephanie Elaine Post and Tracy Lynn Sears

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Design and Fabrication of a Novel Cell-Derived Matrix Scaffold for Dermal Wound Healing, Fioleda Prifti Kesseli, Jennifer Lee Cooper, and Sarah Phyllis Mattessich

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FancJ Acetylation as a DNA Damage Response, Steven Quan

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Investigation of Interaction of MIG-10 and ABI-1, Two Proteins Important for Neuronal Migration and Axon Guidance in C. elegans, Andrea Reis-Silvia

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Experimental and Computational Spectroscopic Studies of the Isomers and Conformations of Dibenzylideneacetone, Zachary Brian Richardson

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Subcellular Localization and the Effect on The Oncoapoptotic Capability of Porcine Circovirus Type 1 VP3, Andrew McFarland Rogers and Kenneth P. Hough

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Production of Furanic Liquid Compounds from Cellulosic Biomass Based on Molten Salts and Catalysis, Brian Joseph Scully, John Thomas Rynkar, and Ryan Timothy O'Hara

Major Qualifying Projects from 2011

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Continuous Ethanol Production via a Magnetically Stabilized Bioreactor, Anthony N. Aldi and Craig Peterson Young

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Glucan Particle Delivery of Mesoporous Silica-Drug Nanoparticles, Abaigeal C. Caras and Lindsey Catherine Kut

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Surface Derivatization of Glucan Particles for Drug Delivery, Melissa K. Castle

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Synthesis and Properties of a Visible-to-Near-IR-Fluorescing 2,5-Diarylidene Cyclopentanone Charge-Transfer Dye, Zhen Chen

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Platelet Closure Time in Severe Sepsis and Septic Shock, Nicole Kathryn Comosa and Seanna Marie Reilly

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Substrate Envelope-Based Design of New Dipeptide Isostere Cores for the Development of Protease Inhibitors against Drug-Resistant HIV-1, Jing Fu

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The 
Photophysical
 Properties 
of 
a 
Symmetrically 
Substituted
 2,5
¨C
 Diarylidene
 Cyclopentanone
 Dye:
(2E,5E)©2,5©, Katarina Lynn Lopez

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Prediction of New Pharmacophore Scaffolds, Nicole A. Lounsbury and Raha Moussavi-Aghdam

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Kinetics of Singlet Oxygen Release from Endoperoxides of 2-Pyridone Derivatives, Lan Luo

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Uncoupling the Nuclear Export and Multimerization Mechanisms of Apoptin, Dilasha Mahat and Lauren Nicole D'Elia

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The role of residues 153 and 283 in the non-macrophage-tropic phenotype of HIV-1 R5 envelopes from transmitted viruses, John Raymond Martin

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Construction and Analysis of a Gain-of-Function PCV2 VP3 Isoform Chimera, Andrew Francis Nemeth and Courtney Lynne Gilbert

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A Comparison of Quantum Mechanical Models Applied to α,β Unsaturated Carbonyl Compounds, William Henri Neve

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The role of Cathepsin L in the innate immune system, Alison Genevieve Paquette

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Using Channelrhodopsin-2 to Induce Apoptosis, Amanda Rose Sargent

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Localization of the Human Torque Teno Virus VP3 Protein, Nicholas Paul Stone and Sean Matthew McCauley

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Design and Application of Metal Organic Frameworks, Sahag Voskian

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Design and Synthesis of Crown Ether Ligands for Use in Metal Organic Frameworks, Joshua Michael Wimble

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Subcellular Localization Analysis of Truncation Mutants of Porcine Circovirus 1 VP3, Matija Zelic and Meaghan Hughes Paris

Major Qualifying Projects from 2010

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Nanoparticle-Based Bioanalysis, John S. Austin

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Investigating the Ability of Porcine Circovirus 2 to Selectively Target and Kill Cancer Cells, Krista Marie Baker and Roseann Susan Gammal